Successful outcomes following plastic surgery procedures rest on infection control, wound healing as well as scar reduction. The goal of Fecal Microbiota Transplantation (FMT), a novel therapeutic strategy, is to reestablish the recipient’s gut microbiota by transferring stool from a healthy donor to the patient. FMT has drawn attention in a number of spheres, including dermatology and surgery, despite its historical use in treating Clostridium difficile infections (CDI). Appreciating the role of gut microbiota in infection deterrence, scarring as well as wound healing, may aid plastic surgeons improve surgical results. The current paper surveys the potential uses of FMT in plastic surgery, with emphasis on how it might improve wound care and patient recovery.